Research labs and discovery teams worldwide

Setting

A cell biology lab at a major Scandinavian research university, running longitudinal imaging studies on 3 different ZEISS and Leica confocal systems across two facilities.

The lab's multi-site study was generating inconsistent fluorescence intensity measurements across instruments — making it impossible to pool data from different imaging sessions without manual rescaling.

Cross-instrument CV reduced from ~37% to <7% after Cytely standardization. Data pooled from 3 systems without manual correction.

Setting

A high-content screening team at a European pharmaceutical company, running compound library screens on an Opera Phenix and an ImageXpress Micro Confocal in parallel.

Z' factors on the same assay were consistently 0.08–0.15 lower on one instrument compared to the other, despite identical biological protocols. Root cause traced to illumination non-uniformity in one system.

Cytely's flatfield correction brought Z' factors within 0.03 of each other across both systems. Campaign data now pooled for SAR analysis.

Setting

An imaging core facility at a research institute affiliated with a major European university, providing services to 40+ research groups on 8 different microscopy platforms.

User groups were generating non-comparable intensity measurements depending on which instrument they were assigned to for their experiment — leading to support requests and data interpretation conflicts.

Cytely deployed as a post-acquisition standardization step recommended to all users. Reduced intensity-related support tickets by the core facility team.